IMMUNOMET: EU Working Group on ImmunoMetabolism

Consortium Articles

Team of A Nicoletti: Clement M et al. 2015. Circulation 131:560 (LINK). Abstract BACKGROUND: -The atheromodulating activity of B cells during the development of atherosclerosis is well documented, but the mechanisms by which these cells are regulated have not been investigated. METHODS AND RESULTS: -Here, we analyzed the contribution of […]

Control of the Tfh-GC B Cell Axis by CD8+ Tregs ...

This entry was posted in Consortium Articles on March 7, 2015

Team of Marelli-Berg: Fu H et al. 2014. Nature communications 5:3436 (LINK). Abstract Localization of CD4(+)CD25(+)Foxp3(+) regulatory T (Treg) cells to lymphoid and non-lymphoid tissue is instrumental for the effective control of immune responses. Compared with conventional T cells, Treg cells constitute a minute fraction of the T-cell repertoire. Despite this […]

Self-recognition of the endothelium enables regulatory T-cell trafficking and defines ...

This entry was posted in Consortium Articles on March 7, 2015

Team of L O’Neill : Coll RC et al. 2015. Nat Med 21:248 (LINK). Abstract The NOD-like receptor (NLR) family, pyrin domain–containing protein 3 (NLRP3) inflammasome is a component of the inflammatory process, and its aberrant activation is pathogenic in inherited disorders such as cryopyrin-associated periodic syndrome (CAPS) and complex […]

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment ...

This entry was posted in Consortium Articles on March 6, 2015